Fatty alcohol esters
Medchemexpress LLC BIO-11006 acetate 10mM 1mL | 10MM 1ML
BIO-11006 acetate an analog of the MANS peptide is a MARCKS (myristoylated alanine-rich C kinase substrate) inhibitor[1
Medchemexpress LLC CBP-501 (acetate) | 1929.06 (free base) | 1 MG
CBP-501 acetate is a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate. It inhibits the activity of multiple Ser216-specific kinases, including MAPKAP-K2, C-Tak1, CHK1, and CHK2. It is used for various types of cancer and enhances the cytotoxicity of CDDP and Bleomycin against cancer cells both in vitro and in vivo.
- Inhibits MAPKAP-K2 with an IC50 of 0.9 μM
- Inhibits C-Tak1 with an IC50 of 1.4 μM
- Inhibits Chk1 with an IC50 of 3.4 μM
- Inhibits Chk2 with an IC50 of 6.5 μM
- Stable for 2 years at -80°C as powder
- Stable for 1 year at -20°C as powder
- Stable for 6 months at -80°C in solvent
- Stable for 1 month at -20°C in solvent
- Enhances cytotoxicity of CDDP and Bleomycin
Medchemexpress LLC Furfuryl acetate | 623-17-6 | 98.3% | 140.14 | 25 G
Furfuryl acetate is a laboratory chemical used for the synthesis of substances such as 5-acetoxymethyl-2-vinylfuran and 5-hydroxymethyl-2-vinylfuran. It is intended for research use only and should be handled by qualified personnel in appropriate facilities, as it has not been fully validated for medical applications.
- Used in the synthesis of 5-acetoxymethyl-2-vinylfuran.
- Used in the synthesis of 5-hydroxymethyl-2-vinylfuran.
- Intended for laboratory use.
- Harmful if swallowed.
- Causes skin irritation.
- Causes serious eye irritation.
- May cause respiratory irritation.
Medchemexpress LLC Bio-11006 acetate | 00-00-0 | 99.9% | 1110.22 g/mol | C48H79N13O17 | 50 MG
BIO-11006 acetate is the acetate salt form of a peptide analog of the MANS peptide that inhibits MARCKS (myristoylated alanine-rich C kinase substrate). It is supplied for research use and is available as lyophilized peptide vials or as a ready-to-use aqueous solution.
- Inhibits MARCKS protein by mimicking the MANS peptide.
- Peptide acetate salt format for improved handling and solubility.
- Chemical formula C48H79N13O17.
- Molecular weight 1110.22 g/mol.
- Purity 99.92%.
- Available in multiple pack sizes, including 50 mg and 10 mM 1 mL solution.
- For research use only.
Medchemexpress LLC Resomelagon acetate (AP1189 acetate) | 1809420-72-1 | 99.8% | 358.35 | 50 MG
Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist targeting MC1 and MC3. It induces ERK1/2 phosphorylation and Ca2+ mobilization, and exhibits anti-inflammatory activity. Resomelagon acetate can be used for obesity and chronic inflammation research.
- Potent, orally active melanocortin receptor agonist
- Targets MC1 and MC3
- Induces ERK1/2 phosphorylation and Ca2+ mobilization
- Exhibits anti-inflammatory activity
- Inhibits TNF-α release and efferocytosis
- Promotes resolution of acute inflammation in vivo
- Reduces arthritis in mice
Medchemexpress LLC Ulipristal acetate (CDB-2914) | 126784-99-4 | 99.9% | 475.62 | 1 ML
Ulipristal acetate (CDB-2914) is an orally active, selective progesterone receptor modulator (SPRM). It stimulates the autophagic response selectively in leiomyoma cells and has potential for treating benign gynecological conditions like uterine myoma.
- Orally active.
- Selective progesterone receptor modulator (SPRM).
- Stimulates autophagic response in leiomyoma cells.
- Potential for treating uterine myoma.
Medchemexpress LLC Oxytocin (acetate) | 6233-83-6 | 99.7% | 1067.24 | 100 MG
Oxytocin acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. It functions as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects, especially in the face of adversity or trauma.
- Pleiotropic hypothalamic peptide
- Facilitates parturition, lactation, and prosocial behaviors
- Functions as a stress-coping molecule
- Exhibits anti-inflammatory effects
- Acts as an antioxidant
- Provides protective effects, particularly during adversity or trauma
Medchemexpress LLC KLA seq acetate | 98.1% | 1876.47 (free base) | 1 MG
KLA seq acetate is a cell membrane-penetrating α-helical amphipathic model peptide. It conjugates peptide nucleic acids (PNAs) for delivery to mammalian cells, forming a delivery system that covalently links targeted mRNA and fluorescein. This system exhibits low re-export and is less resistant to serum effects.
- Cell membrane-penetrating alpha-helical amphipathic model peptide
- Conjugates peptide nucleic acids (PNAs) for mammalian cell delivery
- Covalently links targeted mRNA and fluorescein
- Low re-export and reduced serum effects
- Purity: 98.1%
- Molecular weight: 1876.47 (free base)
- Appearance: Solid, white to off-white
- Solubility: ≥ 100 mg/mL in H2O
Medchemexpress LLC SPR741 acetate | 99.4% | 1052.18 | 100 MG
SPR741 acetate is a cationic peptide derived from polymyxin B, functioning as a potentiator molecule. It enhances the permeability of the outer membrane of Gram-negative bacteria, making it useful for treating severe Gram-negative bacterial infections and inhibiting multidrug-resistant Gram-negative bacteria. While it lacks significant antibacterial activity on its own, it increases the accumulation of co-administered antibiotics inside the pathogen and has an improved safety profile compared to polymyxin B.
- Enhances permeability of Gram-negative bacterial outer membrane
- Useful for treating severe Gram-negative bacterial infections
- Inhibits multidrug-resistant Gram-negative bacteria
- Broadens activity spectrum of antibiotics when combined
- Potentiates antibiotics that are substrates of the AcrAB-TolC efflux pump
- Improved safety profile compared to polymyxin B
Medchemexpress LLC Protirelin acetate | 120876-23-5 | 99.9% | 452.46 | 1 ML
Protirelin acetate is a highly conserved neuropeptide that plays a crucial role in the hormonal regulation of thyroid-stimulating hormone (TSH) levels, in addition to exhibiting neuromodulatory functions. It is an evolutionarily ancient neuropeptide, with origins predating the divergence of protostomes and deuterostomes, and may have historically been involved in controlling postembryonic growth and reproduction.
- Investigated for its effect on body temperature in rats.
- Causes a temporary, dose-dependent rise in body temperature in male Wistar rats.
- The hyperthermic action may involve the release of thyroid hormone.
- Thyroidectomized rats do not show a rise in body temperature when administered Protirelin.
Medchemexpress LLC Anrikefon acetate | 2584931-05-3 | 99.7% | 763.97 | 10 MG
Anrikefon acetate is a kappa opioid receptor agonist that exhibits an analgesic effect. This product is strictly for research purposes and is not intended for human or patient use.
- Kappa opioid receptor agonist
- Analgesic effect
- For research use only
- Solid appearance
- White to off-white color
- Soluble in DMSO
Medchemexpress LLC PNC-27 acetate | 99.98% | 4031.73 (free base) | 100 MG
PNC-27 acetate is a chimeric p53-penetratin peptide that binds to HDM-2 in a p53 peptide-like structure.
- Induces selective membrane-pore formation, leading to cancer cell lysis.
- Utilized in acute myeloid leukemia research.
Medchemexpress LLC DT-2 acetate | 98.6% | 3761.25 | 1 MG
DT-2 is a potent and selective inhibitor of the cGMP-dependent protein kinase (PKG), which inhibits PKG catalyzed phosphorylation with a Ki of 12.5 nM.
- Potent and selective inhibitor of cGMP-dependent protein kinase (PKG).
- Inhibits PKG catalyzed phosphorylation.
- For research use only.
Medchemexpress LLC KRpTIRR acetate | 98.2% | 908.99 | 1 MG
KRpTIRR acetate is a phosphothreonine-containing peptide that serves as a substrate for phosphatases.
- Appearance: Solid, white to off-white
- Sequence: Lys-Arg-{Thr
}-Ile-Arg-Arg (KR-{Thr }-IRR) - Solubility in water: Greater than or equal to 100 mg/mL
- Functions as a peptide, enzyme substrate, and phosphatase inhibitor
Medchemexpress LLC Temporin B (acetate) | 99.0% | 1511.89 | 10 MG
Temporin B acetate is an antimicrobial peptide with a molecular weight of 1511.89 and a purity of 99.0%. It is primarily active against Gram-positive bacteria and demonstrates less activity against Gram-negative bacteria.
- Antimicrobial peptide
- Primarily active against Gram-positive bacteria
- Less active against Gram-negative bacteria